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Acetazolamide (diamox): what is it for and side effects

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Diamox is an enzyme inhibitor drug indicated for the control of fluid secretion in certain types of glaucoma, treatment of epilepsy and diuresis in cases of cardiac edema.

This medicine is available in pharmacies, in the dose of 250 mg, and can be purchased for a price of about 14 to 16 reais, upon presentation of a prescription.

How to use

The dosage depends on the problem to be treated:

1. Glaucoma

In open-angle glaucoma, the recommended dose is 250 mg to 1 g per day, in divided doses, for the treatment of closed-angle glaucoma, the recommended dose is 250 mg every 4 hours. Some people respond to 250 mg twice a day on short-term therapy, and in some acute cases, depending on the individual situation, it may be more appropriate to administer an initial dose of 500 mg, followed by doses of 125 mg or 250 mg every 4 hours.

2. Epilepsy

The suggested daily dose is 8 to 30 mg / kg of acetazolamide, in divided doses. Although some patients respond to low doses, the ideal total dose range appears to range from 375 mg to 1 g per day. When acetazolamide is administered in combination with other anticonvulsants, the recommended dose is 250 mg acetazolamide, once a day.

3. Congestive heart failure

The usual recommended starting dose is 250 mg to 375 mg, once a day, in the morning.

4. Drug-induced edema

The recommended dose is 250 mg to 375 mg, once a day, for one or two days, alternating with a day of rest.

5. Acute mountain disease

The recommended dose is 500 mg to 1 g of acetazolamide per day, in divided doses. When the climb is fast, a higher dose of 1 g is recommended, preferably 24 to 48 hours before the climb and continue for 38 hours while at high altitude or for a longer period, as needed to control symptoms.

Who should not use

Acetazolamide should not be used in people who are hypersensitive to the components of the formula, in situations where serum sodium or potassium levels are depressed, in cases of severe kidney and liver dysfunction or disease, adrenal gland failure and in acidosis hyperchloremic.

This medication should also not be used in pregnant or lactating women without the doctor's guidance.

Possible side effects

Some of the most common side effects that can occur during treatment are headache, malaise, fatigue, fever, flushing, stunted growth in children, flaccid paralysis and anaphylactic reactions.

Acetazolamide (diamox): what is it for and side effects