- Protamine Indications
- How to use Protamine
- Side Effects of Protamine
- Protamine contraindications
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Protamine is an injectable medicine, used to neutralize the anticoagulant action of heparin in adults.
Protamine should be administered through the vein by a healthcare professional.
Protamine Indications
Protamine is indicated to neutralize the anticoagulant action of heparin in cases of severe bleeding related to the use of heparin, and to neutralize the effect of heparin administered pre-surgical and during cardiopulmonary bypass, as in dialysis and cardiac surgery.
How to use Protamine
The use of Protamine must be guided by the doctor according to the objective.
Side Effects of Protamine
Side effects of Protamine include drop in blood pressure, decreased heart rate, feeling hot, shortness of breath, nausea, vomiting, tiredness, allergy, bleeding, back pain, respiratory failure, circulatory collapse, capillary leak and acute pulmonary hypertension.
Protamine contraindications
Protamine is contraindicated in patients with hypersensitivity to the components of the formula.
In addition, this medicine should not be used by pregnant women without medical advice.