Lynparza is a drug that contains olaparib, a substance that inhibits the action of an enzyme responsible for repairing the DNA of cells during their multiplication. While normal cells have a mechanism that works in the absence of this enzyme and uses the proteins BRCA 1 and BRCA2, cancer cells in the ovary do not, and therefore cannot multiply, eventually disappearing.
Thus, Lynparza is used to treat ovarian cancer, delaying its development. This medicine can be purchased in conventional pharmacies with a prescription, in the form of 50 mg capsules.
Price
This medication has already been approved for use in Brazil by Anvisa, however, it is not yet on sale.
What is it for
This medication is indicated for the treatment of ovarian cancer, cancer of the fallopian tubes or primary peritoneal cancer with BRCA mutation.
How to take
The recommended dose is 400 mg, that is 8 capsules, 2 times a day, totaling 16 capsules daily. This dose should be started within 8 weeks after platinum chemotherapy.
Before starting treatment with Lynparza, it is necessary to confirm the presence of the BRCA mutation. Therefore, the drug should never be used without the doctor's indication.
Possible side effects
Some of the most common side effects of using this remedy include decreased appetite, headaches, dizziness, reduced taste, nausea, vomiting, diarrhea, shortness of breath and stomach pain.
In addition, it is also common to develop anemia and other changes in the blood test, such as reduced lymphocytes, decreased neutrophils and increased serum creatinine and mean corpuscular volume.
Who should not take
Lynparza is contraindicated for women who are pregnant, breastfeeding or who are allergic to olaparib or any other component of the formula.
