Myalept to treat lipodystrophy

Myalept is a medicine that contains an artificial form of leptin, a hormone produced by fat cells and that acts on the nervous system regulating the sensation of hunger and metabolism, and is therefore used to treat the consequences in patients with low fat, as in the case of congenital lipodystrophy, for example.

Myalept contains metreleptin in its composition and can be purchased in the United States with a prescription, in the form of subcutaneous injection, similar to insulin pens.

Myalept indications

Myalept is indicated as replacement therapy in patients with complications caused by a lack of leptin, as in the case of acquired or congenital generalized lipodystrophy.

How to use Myalept

How to use Myalept varies according to the patient's weight and sex, with general guidelines including:

Body weight 40 kg or less: initial dose of 0.06 mg / kg / day, which can be increased to a maximum of 0.13 mg / kg / day; Men over 40 kg: initial dose of 2.5 mg / kg / day, which can be increased to a maximum of 10 mg / kg / day; Women over 40 kg: initial dose of 5 mg / kg / day, which can be increased to a maximum of 10 mg / kg / day.

Therefore, the dose of Myalept should always be indicated by an endocrinologist. Myalept is given with an injection under the skin, so it is important to receive guidance from a doctor or nurse on how to use the injection.

Side effects of Myalept

The main side effects of Myalept include headaches, weight loss, abdominal pain and reduced blood sugar levels, which can cause easy tiredness, dizziness and cold sweats.