Baricitinib is a substance that reduces the response of the immune system, decreasing the action of enzymes that promote inflammation and the appearance of joint damage in cases of rheumatoid arthritis. Thus, this remedy is able to reduce inflammation, relieving the symptoms of the disease such as pain and swelling of the joints.
However, this drug is not yet approved in Brazil by Anvisa, nor in the United States by the FDA, and it can only be purchased in Europe with a prescription, in the form of 2 and 4 mg tablets.
What is it for
Baricitinib is indicated for the treatment of moderate to severe rheumatoid arthritis, in cases where the symptoms do not improve with the use of other antirheumatic drugs.
How to take
Treatment with baricitinib should always be guided by a doctor, however, the recommended starting dose is 4 mg once a day.
However, this dose can be reduced to 2 mg per day, when inflammation is controlled.
Possible side effects
The use of this remedy can cause the appearance of some side effects like nausea, acne, weight gain and more frequent appearance of respiratory infections. In addition, some patients may also experience changes in the blood test, especially in the number of platelets and neutrophils.
Who should not use
Baricitinib is contraindicated for pregnant women and people with hypersensitivity to any of the components of the formula.
In addition, this medication should be used with caution, and to a lesser extent, in elderly children and patients with liver or kidney disease.
