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Squamous cell carcinoma of the skin: symptoms and treatment

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Skin cancers are divided into two major groups, melanoma and non-melanoma. Non-melanoma tumors include basal cell carcinomas and squamous cell carcinomas, which represent the majority of malignant skin tumors.

Squamous cell carcinoma of the skin represents the second most common type of skin cancer. This cancer appears in the squamous cells, which form the epidermis and can manifest itself in all parts of the body, including the mucous membranes and genitals, although they develop more frequently in areas more exposed to the Sun.

The treatment options are diverse and depend on the size, location and depth of the tumor, the person's age and general health conditions.

What are the signs and symptoms

Squamous cell carcinoma of the skin occurs most often on skin exposed to the sun, such as the scalp, hands, ears or lips. The signs and symptoms that may occur are the appearance of a firm, red lump, a wound with a scaly crust or pain and roughness in an old scar or ulcer.

In addition, there may also be a rough, scaly stain on the lip that can develop into an open sore, a painful or rough red ulcer inside the mouth or the appearance of a wart-like sore on the anus or genitals.

What are the risk factors

Although it is believed that this type of cancer can be hereditary and appear spontaneously, the cases in which there is a greater tendency to develop squamous cell carcinoma are:

  • Having light skin and hair or blue, green or gray eyes; Frequent exposure to the sun, especially in the hottest hours; Having a history of basal cell carcinoma; Having a disease called xeroderma pigmentosa. Learn more about this disease; Being over 50;

In addition, this disease is more common in men than women.

Possible causes

The most frequent causes of squamous cell carcinoma of the skin are chronic exposure to sunlight, frequent use of tanning beds and skin wounds, as cancer can appear in burns, scars, ulcers, older wounds and in parts of the body previously exposed to X-rays or other chemicals.

In addition, it can also develop from chronic infections and inflammations on the skin or in people with HIV, autoimmune diseases or people who are undergoing or have undergone chemotherapy and certain medications that make the immune system weaker, decreasing resistance diseases and increasing the risk of developing skin cancer.

How the treatment is done

If treated early, the squamous cell carcinoma of the skin can be cured, otherwise these tumors can invade the tissues around the cancer and disfigure the skin, and can also create metastases and reach other organs, which can lead to death. Treatment must be adapted to the type, size, location and depth of the tumor, the person's age and general health conditions.

There are several ways to treat squamous cell carcinoma of the skin:

1. Mohs surgery

This technique consists in removing the visible part of the tumor, which is being examined under a microscope, and the procedure is repeated until the last tissue removed is free of tumor cells. After removal, the wound can heal normally or be reconstructed with plastic surgery.

2. Excisional surgery

With this procedure, all the cancerous tissue is removed, as well as a skin border around the lesion, as a safety margin. The wound is closed with stitches and the removed tissue is sent for analysis, to verify that all cancer cells have been removed.

3. Curettage and electrodissection

In this procedure, the cancer is scraped with an instrument called a curette, and then an electro cauterizing needle is used that destroys the malignant cells and controls the bleeding. This procedure is usually repeated more often, to ensure that all cancer cells have been eliminated.

This procedure is not considered effective in more invasive and aggressive carcinomas or cancer in critical areas, such as the eyelids, genitals, lips and ears.

4. Cryosurgery

In cryosurgery, the tumor is destroyed by freezing the tissue with liquid nitrogen, without the need for cuts or anesthesia. The procedure may have to be repeated several times, so that all malignant cells are destroyed.

This method is not widely used to treat more invasive cancers, as it is not as effective in deeper regions of the tumor.

5. Radiotherapy

In this procedure, X-rays are applied directly to the lesion, and anesthesia or cutting is also unnecessary, however, it is necessary to carry out a series of treatments, administered several times over a period of about one month.

Radiotherapy is indicated for tumors that are difficult to treat through surgery or for situations in which it is not recommended.

6. Photodynamic therapy

Photodynamic therapy is most commonly used in people whose cancer develops on the face or scalp. In this procedure, 5-aminolevulinic acid is used, which is applied to the lesions and the next day a strong light is used. This treatment destroys the carcinoma cells without causing damage to normal tissue.

7. Laser surgery

In this technique, a laser is used to remove the outer layer of the skin and varying amounts of deeper skin, without bleeding. The risks of scarring and loss of pigment are slightly higher than in other techniques, and the recurrence rates are similar to those of photodynamic therapy.

Squamous cell carcinoma of the skin: symptoms and treatment