- What is it for
- How to take
- 1. Vonau flash oral disintegration tablets
- 2. Vonau for injection
- Who should not use
- Possible side effects
- 1. Vonau flash tablets
- 2. Vonau for injection
Ondansetron is the active substance in an antiemetic medicine known commercially as Vonau. This medication for oral and injectable use is indicated for the treatment and prevention of nausea and vomiting, since its action blocks the vomiting reflex, reducing the feeling of nausea.
What is it for
Vonau flash is available in tablets of 4 mg and 8 mg, which have ondansetron in its composition that acts to prevent and treat nausea and vomiting in adults and children over 2 years of age.
Injectable Vonau is available in the same doses as ondansetron and is indicated for the control of nausea and vomiting induced by chemotherapy and radiotherapy in adults and children from 6 months of age. In addition, it is also indicated for the prevention and treatment of nausea and vomiting in the postoperative period, in adults and children from 1 month of age.
How to take
1. Vonau flash oral disintegration tablets
The tablet must be removed from the packaging and placed immediately on the tip of the tongue so that it dissolves in seconds and is swallowed, without the need to drink the medicine with liquids.
Prevention of nausea and vomiting in general:
Adults: The recommended dose is 2 tablets of 8 mg.
Children over 11 years old: The recommended dose is 1 to 2 4 mg tablets.
Children aged 2 to 11 years: The recommended dose is 1 4 mg tablet.
Prevention of postoperative nausea and vomiting:
The dose to be used should be the one previously described for each age, and should be taken 1 h before induction of anesthesia.
Prevention of nausea and vomiting in general associated with chemotherapy:
In cases of chemotherapy that causes severe vomiting, the recommended dose is 24 mg Vonau in a single dose, which is equivalent to 3 8 mg tablets, 30 minutes before the start of chemotherapy.
In cases of chemotherapy that causes moderate vomiting, the recommended dose is 8 mg of ondansetron, twice a day when the first dose should be administered 30 minutes before chemotherapy, and the second dose should be administered 8 hours later.
For one or two days after the end of chemotherapy, it is recommended to take 8 mg ondansetron, twice a day every 12 hours.
For children aged 11 years and over, the same dose proposed for adults is recommended and for children aged 2 to 11 years of age 4 mg of ondansetron is recommended 3 times daily for 1 or 2 days after end of chemotherapy.
Prevention of nausea and vomiting associated with radiotherapy:
For total irradiation of the body the recommended dose is 8 mg of ondansetron, 1 to 2 hours before each fraction of radiotherapy applied each day.
For radiotherapy of the abdomen in a single high dose, the recommended dose is 8 mg ondansetron, 1 to 2 hours before radiotherapy, with subsequent doses every 8 hours after the first dose, for 1 to 2 days after the end of radiotherapy.
For radiotherapy of the abdomen in divided daily doses, the recommended dose is 8 mg of ondansetron, 1 to 2 hours before radiotherapy, with subsequent doses every 8 hours after the first dose, each day of radiotherapy application.
For children aged 2 to 11 years, a dose of 4mg of ondansetron is recommended 3 times a day. The first should be administered 1 to 2 hours before the start of radiotherapy, with subsequent doses every 8 hours after the first dose. It is recommended to administer 4 mg of ondansetron, 3 times a day for 1 to 2 days after the end of radiotherapy.
2. Vonau for injection
Injectable Vonau must be administered by a healthcare professional and the selection of the dose regimen should be determined by the severity of nausea and vomiting.
Adults: The recommended intravenous or intramuscular dose is 8 mg, administered immediately before treatment.
Children and adolescents from 6 months to 17 years of age: The dose in cases of nausea and vomiting induced by chemotherapy can be calculated based on body surface area or weight.
This dose can be changed by the doctor, depending on the severity of the situation.
Who should not use
This medicine should not be used by people allergic to the active substance or any of the components contained in the formula, in pregnant or breastfeeding women and in children under 2 years of age.
One should also avoid the use of ondansetron in patients with congenital long QT syndrome and use it with caution in people with kidney or liver problems. In addition, Vonau whose presentation is in tablets should be used with caution in phenylketonurics due to the excipients contained in the formula.
Possible side effects
1. Vonau flash tablets
The most common side effects that occur with the use of Vonau flash pills are diarrhea, constipation, headache, and tiredness.
In addition and less frequently, discomfort and the appearance of wounds may also occur. If symptoms such as feeling uneasy, agitation, redness of the face, palpitations, itching, pulse in the ear, coughing, sneezing, difficulty breathing in the first 15 minutes of administering the medication, it is necessary to seek medical help urgently.
2. Vonau for injection
The most common side effects that can occur with the use of injectable Vonau are sensation of heat or redness, constipation and reactions at the site of the intravenous injection.
Less frequently, seizures, movement disorders, arrhythmias, chest pain, decreased heart rate, hypotension, hiccups, asymptomatic increase in functional liver tests, allergic reactions, dizziness, transient visual disturbances, prolongation of the QT interval, transient blindness and toxic rash.
