Zytiga is a medicine used in the treatment of prostate cancer that has as its active ingredient abiraterone acetate. Abiraterone inhibits a substance necessary for the production of hormones that regulate male characteristics, but which are also related to the increase in cancer. Thus, this medicine prevents the progression of the tumor in the prostate, increasing life expectancy.
Although Zytiga's abiraterone causes the adrenal glands to produce more natural corticosteroids, it is common for the doctor to also recommend corticosteroid drugs together to help decrease prostate inflammation and improve symptoms, such as difficulty urinating or the feeling of full bladder, for example.
This medicine is available in 250 mg tablets and its average price is 10 to 15 thousand reais per package, but it is also included in the SUS drug list.
What is it for
Zytiga is indicated for the treatment of prostate cancer in adult men when the cancer is spread through the body. It can also be used in men who have not improved their disease after castration to suppress the production of sex hormones or after chemotherapy with docetaxel.
How to use
How to use Zytiga consists of taking 4 250 mg tablets in a single dose, approximately 2 hours after a meal. No food should be eaten for at least 1 hour after use. Do not exceed the maximum daily dose of 1000 mg.
Zytiga is also usually taken in combination with 5 or 10 mg of prednisone or prednisolone, twice a day, according to the doctor's guidance.
Possible side effects
The use of this medication can lead to the appearance of some side effects, the most common of which may include:
- Swelling of the legs and feet; Urinary tract infection; Increased blood pressure; Increased levels of blood fat; Increased heart rate; Chest pain; Heart problems; Diarrhea; Red spots on the skin.
There may also be a reduction in potassium levels in the body, leading to the appearance of muscle weakness, cramps and heart palpitations.
Generally, this medicine is used with the supervision of a doctor or a health professional, such as a nurse, who will be alert to the appearance of any of these effects, initiating the appropriate treatment, if necessary.
Who should not take
Zytiga is contraindicated in people who are hypersensitive to abiraterone or any component of the formula, as well as patients with severe liver failure. It should not be administered to pregnant women or while breastfeeding.