PFAPA syndrome is a rare genetic disease that manifests itself during early childhood up to the age of five. In this syndrome the child develops monthly symptoms such as fever, foot-and-mouth disease or pharyngitis and adenitis.
This disease is benign and children who suffer from it experience periods of fevers that last three to five days at 28-day intervals. Between periods of fever the child is healthy and develops normally. Symptoms decrease with advancing age and children with the disease do not have long-term sequelae.
Treatment is done with the medication prednisone to improve symptoms.
