Dent's disease is a rare genetic problem that affects the kidneys, causing a greater number of proteins and minerals to be eliminated in the urine that can lead to the frequent appearance of kidney stones or other more serious problems, such as kidney failure.
Generally, Dent's disease is more common in men, but it can also occur in women, presenting milder symptoms.
Dent's disease has no cure, but there are some treatments that help to reduce symptoms and prevent injuries that cause the development of more serious kidney problems.
Dent disease symptoms
The main symptoms of Dent's disease are:
- Frequent kidney attacks; Blood in the urine; Dark colored urine and foam.
These symptoms usually appear during childhood and worsen over time, especially when treatment is not done properly.
In addition, Dent's disease can also be identified in the urine test when there is an exaggerated increase in the amount of protein or calcium, with no apparent cause.
Treatment for Dent's disease
Treatment for Dent's disease should be guided by a nephrologist and usually aims to reduce the symptoms of patients through the ingestion of diuretics, such as Metolazone or Indapamide, which prevent the excessive elimination of minerals, preventing the appearance of kidney stones, for example.
However, as the disease progresses, other problems may arise, such as kidney failure or weakening of the bones, which require specific treatment, ranging from vitamin intake to dialysis.