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Entresto: what it is for and how to use it

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Entresto is a drug indicated for the treatment of symptomatic chronic heart failure, which is a condition in which the heart is unable to pump blood with sufficient strength to supply the necessary blood to the entire body, leading to symptoms such as shortness of breath. and swelling in the feet and legs due to the accumulation of fluid.

This medicine contains in its composition valsartan and sacubitril, available in dosages 24 mg / 26 mg, 49 mg / 51 mg and 97 mg / 103 mg, and can be purchased in pharmacies, upon presentation of a prescription and for a price of about 96 to 207 reais.

What is it for

Entresto is indicated for the treatment of chronic heart failure, especially in cases where there is a high risk of hospitalization or even death, reducing this risk.

How to take

The generally recommended dose is 97 mg / 103 mg twice a day, one tablet in the morning and one tablet in the evening. However, the doctor may indicate a lower initial dose, 24 mg / 26 mg or 49 mg / 51 mg, twice a day, and only then increase the dose.

The tablets should be swallowed whole, with the help of a glass of water.

Who should not take

This medicine should not be used by people who are hypersensitive to any of the components of the formula, in people who are taking other drugs for the treatment of hypertension or heart failure, such as angiotensin-converting enzyme inhibitors and in people with a family history reaction to medications such as enalapril, lisinopril, captopril, ramipril, valsartan, telmisartan, irbesartan, losartan or candesartan, for example.

In addition, Entresto should also not be used by people with severe liver disease, a previous history of hereditary angioedema, type 2 diabetes, during pregnancy, breastfeeding or in children under the age of 18 years.

Possible side effects

Some of the side effects that may occur during treatment with Entresto are decreased blood pressure, increased blood potassium levels, reduced kidney function, cough, dizziness, diarrhea, low level of red blood cells, tiredness, kidney failure, headache, fainting, weakness, feeling sick, gastritis, low blood sugar.

If adverse reactions such as swelling of the face, lips, tongue and / or throat with difficulty breathing or swallowing occur, one should stop taking the medication and speak to the doctor immediately.

Entresto: what it is for and how to use it