- Indications of Amphotericin B
- Side effects of Amphotericin B
- Contraindications for Amphotericin B
- How to use Amphotericin B
Amphotericin B is an antifungal medication known commercially as Fungizon.
This drug is for injectable use that acts by preventing the mechanism of action of fungi, since it alters the permeability of its membrane, thus decreasing the likelihood of complications in diseases such as leishmaniasis and candidiasis.
Amphotericin B may be the only effective medication used to treat fatal fungal diseases.
Indications of Amphotericin B
Leishmaniasis; cryptococcal meningitis; aspergillosis; blastomycosis; candidiasis; cryptococcosis; fungal endorecatitis; histoplasmosis; mucormycosis; sporotrichosis; urinary yeast infection.
Side effects of Amphotericin B
Blood changes; Headache; fever; chills; nausea; kidney problems; vomiting.
Contraindications for Amphotericin B
Pregnancy risk B; lactating women; Hypersensitivity to the product.
How to use Amphotericin B
Injectable Use
Adults and Teens
- The amount of Amphotericin B administered depends on the tolerance to the product and the severity of the fungal infection. It is recommended to administer a test dose of 1 mg in 20 ml of glucose solution intravenously for 30 minutes, this procedure must be performed to observe any adverse reaction of the patient. Treatment is usually started with daily administration of 0.25 mg per patient body weight, administered over a period of 2 to 6 hours.
Caution: The maximum dose given by an adult should be 50 mg.
