Focal nodular hyperplasia is a benign tumor about 5 cm in diameter, located in the liver, being the second most common benign liver tumor which, although occurring in both sexes, is more frequent in females, in women 20 and 50 years old.
Generally, focal nodular hyperplasia is asymptomatic and does not require treatment, however, one should visit the doctor regularly in order to monitor its evolution. In most cases, the lesions remain stable in number and size and the disease progression is rarely seen.
Possible causes
Focal nodular hyperplasia may result from an increase in the number of cells in response to an increase in blood flow in an arterial malformation.
In addition, it is thought that the use of oral contraceptives may also be associated with this disease.
What are the signs and symptoms
Focal nodular hyperplasia is usually about 5 cm in diameter, although it can rarely reach more than 15 cm in diameter.
This tumor is usually asymptomatic, and in most cases it is found accidentally on imaging exams. Although it is very rare, it can eventually cause acute symptoms due to bleeding.
How the treatment is done
In asymptomatic people, with typical characteristics demonstrated in imaging tests, it is not necessary to undergo treatment.
Since focal nodular hyperplasia is a benign tumor without a malignant potential, surgical removal should only be performed in situations where there are doubts in the diagnosis, in evolutionary lesions or in people who have any symptoms.
In addition, in women who use contraceptives, interruption of oral contraceptive use is recommended, since contraceptives may be associated with tumor growth.
