Tofacitinib Citrate, also known as Xeljanz, is a medicine to treat rheumatoid arthritis, which allows relief of pain and inflammation in the joints.
This compound acts inside the cells, inhibiting the activity of certain enzymes, the JAK kinases, which prevents the production of specific cytokines. This inhibition reduces the inflammatory response of the immune system, thereby reducing inflammation of the joints.
Indications
Tofacitinib Citrate is indicated for the treatment of moderate to severe active rheumatoid arthritis in adult patients who have not responded to other treatments.
How to take
You should take 1 tablet of Tofacitinib Citrate 2 times a day, which can be taken alone or in combination with other drugs for rheumatoid arthritis, such as methotrexate, for example.
Tofacitinib Citrate tablets should be swallowed whole, without breaking or chewing and together with a glass of water.
Side effects
Some of the side effects of Tofacitinib Citrate can include infection in the nose and pharynx, pneumonia, herpes zoster, bronchitis, flu, sinusitis, urinary tract infection, pharynx infection, changes in blood test results and increased liver enzymes, weight gain, abdominal pain, vomiting, gastritis, diarrhea, nausea, poor digestion, increased blood fat and altered cholesterol, pain in muscles, tendons or ligaments, joint pain, anemia, fever, excessive tiredness, swelling in the extremities of the body, headache, difficulty sleeping, high blood pressure, shortness of breath, cough or hives on the skin.
Contraindications
Tofacitinib Citrate is contraindicated for children and adolescents under the age of 18, patients with severe liver disease and for patients with an allergy to Tofacitinib Citrate or other components of the formula.
In addition, it should not be used by pregnant women or breastfeeding women without a doctor's recommendation.
