DMAA is a substance present in the composition of some dietary supplements, being widely used as a pre-workout by people who practice physical activities, since this substance is able to promote fat loss and ensure greater energy to perform the exercise.
Although it may assist the weight loss process, the distribution, commercialization, dissemination and use of products containing DMAA has been suspended by ANVISA since 2013 due to the fact that it acts directly on the central nervous system and increases the risk of developing heart, liver and kidney diseases, for example. example.
In addition, chronic or high doses of this substance can cause addiction, so it is recommended that products that contain DMAA in their composition should not be consumed.
Side effects of DMAA
The side effects of DMAA are mainly associated with consumption in high doses, in a chronic way and associated with other stimulating substances, such as alcohol or caffeine, for example.
The main mechanism of action of DMAA is vasoconstriction, so the adverse effects of frequent use of DMAA start with a sudden increase in pressure, in addition to the following:
- Severe headache; Nausea; Agitation; Seizures; Cerebral hemorrhage or stroke; Kidney failure; Liver damage; Heart disorders; Dehydration.
Although DMAA was originally included in some dietary supplements, it is contraindicated for human use due to its serious health effects.
How DMAA works
The mechanism of action of DMAA is still widely discussed, however it is believed that this substance acts as a central nervous system stimulant and leads to increased production of norepinephrine and dopamine. The greater amount of circulating norepinephrine stimulates the breakdown of fat molecules, providing extra energy for physical activity and aiding the weight loss process.
In addition, the increase in the amount of circulating dopamine decreases the feeling of tiredness, increases the focus during training and increases gas exchange, providing a greater amount of oxygen to the muscles.
However, due to its action on the nervous system, it is possible that the frequent and high use of this substance, especially when consumed in conjunction with other stimulating substances such as caffeine, for example, can result in dependence and liver failure and cardiac changes, for example.
