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Chlorhexidine: what it is, what it is for and side effects

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Chlorhexidine is a substance with antimicrobial action, effective in controlling the proliferation of bacteria on the skin and mucous membranes, being a product widely used as an antiseptic to prevent infections.

This substance is available in several formulations and dilutions, which must be adapted to the purpose for which they are intended, upon the recommendation of the physician.

How it works

Chlorhexidine, at high dosages, causes the precipitation and coagulation of cytoplasmic proteins and bacterial death and, at lower doses, leads to a change in the integrity of the cell membrane, which results in an extravasation of low molecular weight bacterial components

What is it for

Chlorhexidine can be used in the following situations:

  • Cleaning the newborn's skin and umbilical cord to prevent infections; Maternal vaginal washing in obstetrics; Hand disinfection and skin preparation for surgery or invasive medical procedures; Cleaning and disinfection of wounds and burns; Oral washing in periodontal disease and disinfecting the mouth to prevent pneumonia associated with mechanical ventilation; preparing dilutions for cleaning the skin.

It is very important that the person knows that the dilution of the product must be adapted for the purpose for which it is intended, and should be recommended by the doctor.

Products with chlorhexidine

Some examples of topical products that have chlorhexidine in their composition are Merthiolate, Ferisept or Neba-Sept, for example.

For oral use, chlorhexidine is present in lower amounts and generally associated with other substances, in the form of gel or rinse. Some examples of products are Perioxidin or Chlorclear, for example.

Possible side effects

Although well tolerated, chlorhexidine can, in some cases, cause skin rash, redness, burning, itching or swelling at the application site.

In addition, if used orally, it can cause stains on the surface of the teeth, leave a metallic taste in the mouth, a burning sensation, loss of taste, peeling of the mucosa and allergic reactions. For this reason, prolonged use should be avoided.

Who should not use

Chlorhexidine should not be used in people who are hypersensitive to the components of the formula and should be used with care in the periocular region and ears. In case of contact with eyes or ears, wash with plenty of water.

In addition, it should also not be used by pregnant women without medical advice.

Chlorhexidine: what it is, what it is for and side effects